Accutane / Isotretinoin — Before & After

Oral retinoid for severe acne — often dramatically clears skin over 4–6 months.

What is accutane / isotretinoin?

Oral retinoid for severe acne — often dramatically clears skin over 4–6 months.

Also known as isotretinoin, roaccutane.

Accutane / Isotretinoin by topic

Information pages — cost, recovery, surgeons, and more

Accutane / Isotretinoin by recovery timeline

How the result evolves over time

Accutane / Isotretinoin by demographic

Age and gender breakdowns of common candidates

Accutane / Isotretinoin by ethnicity

Anatomical and aesthetic considerations across patient backgrounds

Accutane / Isotretinoin by outcome reality

Range of results — from natural to cautionary

Accutane / Isotretinoin by where it's performed

Regional approaches and aesthetic preferences

Frequently asked

How long is an Accutane course?

Typically 5–6 months at a target cumulative dose of 120–150 mg/kg. Some patients need a second course; about 70% achieve durable clearance after one course.

What is iPLEDGE?

The FDA-mandated risk management program for isotretinoin in the US. Required monthly office visits, monthly bloodwork, and (for women of childbearing potential) two effective forms of contraception plus monthly pregnancy tests. Designed to prevent fetal exposure given isotretinoin's severe teratogenicity.

Does Accutane cause depression?

Debated. Most epidemiological studies don't find a causal link, but FDA labeling reflects ongoing concern and patient reports. Severe acne itself is associated with depression — improvement often coincides with mood improvement. Discuss any pre-existing mood issues with your prescriber before starting.

Will my acne come back after Accutane?

About 70% of patients achieve durable clearance after one course. About 30% need a second course or maintenance therapy (topical retinoids, spironolactone for women). Hormonal-pattern adult acne tends to recur more than teen acne.

Can I get Accutane online?

Telehealth platforms can prescribe isotretinoin in iPLEDGE-compliant ways — virtual visits with appropriate labwork and pregnancy testing through a participating lab. Quality of supervision varies; for severe cases, in-person dermatology follow-up is the gold standard.